Originally posted by Pooka1
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However we know that infections cause spinal deformity. Polio, Tuberculosis, Vertebral Osteomyelitis and no doubt many other infections that enter the vertebrae cause Scoliosis.
In addition Pulmonary Nontuberculous Mycobacterial Disease and Hyper-IgE syndrome are associated with Scoliosis.
We also know that in the Zebrafish model of Scoliosis the disease is caused by inflammation and can be treated with simple anti-inflammatory drugs.
Based on that information I have a high degree of confidence that AIS will share some similarities with what we already know. Idiopathic Scoliosis is probably caused by some type of inflammation, infection or some combination of the two. Maybe I'll be wrong but it's a safe bet because it's based on science that's already been proven.
As far as heredity is concerned it doesn't make sense to me that natural selection would favor a common, childhood spinal deformity. Children and young adults are supposed to be healthy. That's biology 101 stuff.
But of course nobody knows for sure so I guess we'll have to check back in 5 or 10 years and see who bet correctly.
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