Originally posted by Pooka1
View Post
http://hmg.oxfordjournals.org/conten...mg.ddq571.full
Genetic contributions to AIS have been described for decades (10). About one quarter of AIS patients report a positive family history of disease, and twin studies have consistently supported shared genetic factors in disease (reviewed in 4,5).
Or here:
Adolescent idiopathic scoliosis (IS) is the most common spine deformity arising during childhood, but the etiology of IS remains unknown. A large proportion (75%) of structural scoliosis is clinically classified as idiopathic [1]. Idiopathic scoliosis often appears in several members of the same family, this strongly suggesting a genetic transmission. Clinical studies indicate that approximately 1:4 of the total scoliosis cases and 1:3 of idiopathic scoliosis cases are familial [2].
http://www.scoliosisjournal.com/content/1/1/21
Comment