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Thread: Breast Cancer due to radiation exposure?

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  1. #1
    Join Date
    Mar 2010
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    2,748

    Breast Cancer due to radiation exposure?

    I was just wondering if breast cancer is more common among us scoli people due to repeated radiation exposure? I've read on some other threads that some of you have battled breast cancer - and thankfully won! I'm having a biopsy today and just thought about all of the unprotected x-rays I've had throughout the years, yes it listed that as a risk factor. Any insight?

  2. #2
    Join Date
    Oct 2008
    Location
    Sunshine Coast, Queensland, Australia
    Posts
    3,263
    I don't know rohrer, but want to wish you well. I've had a biopsy too (years before surgery) and it was fine. Let us know how you go.
    Surgery March 3, 2009 at almost 58, now 63.
    Dr. Askin, Brisbane, Australia
    T4-Pelvis, Posterior only
    Osteotomies and Laminectomies
    Was 68 degrees, now 22 and pain free

  3. #3
    Join Date
    Sep 2003
    Location
    Northern California
    Posts
    7,187
    It's been awhile, but there have been other threads on the topic. You might want to do a search using the link above.

    Hope your biopsy is negative.

    Linda
    Never argue with an idiot. They always drag you down to their level, and then they beat you with experience. --Twain
    ---------------------------------------------------------------------------------------------------------------------------------------------------
    Surgery 2/10/93 A/P fusion T4-L3
    Surgery 1/20/11 A/P fusion L2-sacrum w/pelvic fixation

  4. #4
    Join Date
    Apr 2009
    Posts
    1,251
    rohrer - wishing you the best for a clean biopsy. cancer is fairly multi factorial, where have we heard that phrase before eh? While radiation is a risk factor, it is also used for curative purposes, to kill cancer cells. If you search you can even find recent study supporting vitamin D deficiency as a risk factor for the progression of several cancers, including colorectal, melanoma, lung and breast cancer. Hopefully all who must be exposed to xray due to scoliosis, go to facilities that use proper shielding to help reduce any risk involved. Everybody is different and i guess that would mean everyone responds differently to exposure. Keeping you in my prayers.

  5. #5
    Join Date
    Sep 2003
    Location
    NJ
    Posts
    1,293

    Arrow Radiation and breast CA

    As Linda mentioned there have been other posts about this and I remember studies suggesting a higher incidence in persons with scoliosis. In my case, since the scoliosis began around age 11, that's when I began the x-ray monitoring. I never had breast shielding, x-rays may have given higher doses, had more "scatter" and that is the time when breasts are developing.

    I did not want radiation for my recent early breast CA because it would negatively impact my breathing capacity and I would still need mammos ultrasounds and MRIs the rest of my life. I also figured in my mind that since I grew cancer in one breast I would be capable of growing it in the other. I elected a bilateral simple mastectomy with reconstruction. Fortunately I had negative nodes and was stage 1 but I had a total of 3 breast tumors.
    In the lab they found another cancer in the opposite "good" breast!!!! This did not show up aon any diagnostoc test and was not felt as was none of my other tumors.

    My other strong risk factor was 8 years of hormone replacement therapy. I actually didn't want it but, because of the scoliosis, the doctors urged it. Now science says it doesn't really help bone that much and causes earlier dementia, strokes and cardiac disease!!! That is why the large Nurses Study was aborted before it was scheduled to be completed.

    My vit D levels were very good the last 8 years because my bone doctor monitors this regularly.
    Last edited by Karen Ocker; 03-08-2011 at 09:15 PM.
    Original scoliosis surgery 1956 T-4 to L-2 ~100 degree thoracic (triple)curves at age 14. NO hardware-lost correction.
    Anterior/posterior revision T-4 to Sacrum in 2002, age 60, by Dr. Boachie-Adjei @Hospital for Special Surgery, NY = 50% correction

  6. #6
    Join Date
    May 2010
    Location
    Indianapolis area
    Posts
    970
    My local surgeon said that studies have NOT shown a higher incidence of cancer among scoliosis patients. But just to make sure, I would insist on the protective coverings! (Wish I'd know about those when I was a teen.)

    Evelyn
    age 48
    80* thoracolumbar; 40* thoracic
    Reduced to ~16* thoracolumbar; ~0* thoracic
    Surgery 3/14/12 with Dr. Lenke in St. Louis, T4 to S1 with pelvic fixation
    Broken rods 12/1/19; scheduled for revision fusion L1-L3-4 with Dr. Lenke 2/4/2020
    Not "confused" anymore, but don't know how to change my username.

  7. #7
    Join Date
    Sep 2003
    Location
    NJ
    Posts
    1,293

    Have your doctor read this recent large study

    Cancer mortality among women frequently exposed to radiographic examinations for spinal disorders.
    Ronckers CM, Land CE, Miller JS, Stovall M, Lonstein JE, Doody MM.

    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20852, USA.

    Abstract
    We studied cancer mortality in a cohort of 5,573 women with scoliosis and other spine disorders who were diagnosed between 1912 and 1965 and were exposed to frequent diagnostic X-ray procedures. Patients were identified from medical records in 14 orthopedic medical centers in the United States and followed for vital status and address through December 31, 2004, using publicly available regional, state and nationwide databases. Causes of death were obtained from death certificates or through linkage with the National Death Index (NDI). Statistical analyses included standardized mortality ratios (SMR = observed/expected) based on death rates for U.S. females and internal comparisons using Cox regression models with attained age as the time scale. Diagnostic radiation exposure was estimated from radiology files for over 137,000 procedures; estimated average cumulative radiation doses to the breast, lung, thyroid and bone marrow were 10.9, 4.1, 7.4 and 1.0 cGy, respectively. After a median follow-up period of 47 years, 1527 women died, including 355 from cancer. Cancer mortality was 8% higher than expected (95% CI = 0.97-1.20). Mortality from breast cancer was significantly elevated (SMR = 1.68; 95% CI: 1.38-2.02), whereas death rates from several other cancers were below expectation, in particular lung (SMR = 0.77), cervical (SMR = 0.31), and liver (SMR = 0.17). The excess relative risk (ERR) for breast cancer mortality increased significantly with 10-year lagged radiation dose to the breast (ERR/Gy = 3.9; 95% CI: 1.0-9.3).

    PMID: 20681802 [PubMed - indexed for MEDLINE]
    Original scoliosis surgery 1956 T-4 to L-2 ~100 degree thoracic (triple)curves at age 14. NO hardware-lost correction.
    Anterior/posterior revision T-4 to Sacrum in 2002, age 60, by Dr. Boachie-Adjei @Hospital for Special Surgery, NY = 50% correction

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