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Thread: Post-surgery use of SSRI (Lexapro)

  1. #1
    Join Date
    Aug 2005
    Location
    Metro-Detroit, Michigan
    Posts
    138

    Post-surgery use of SSRI (Lexapro)

    Howdy - I finally admitted I need help, and went to my primary care provider regarding my anxiety issues. (I have been having anxiety attacks, especially after the pulmonary embolism.) She prescribed me Lexapro, which is an SSRI. I think that stands for supressed seratonin reuptake inhibitor? Anyway, the patient pamphlet cautioned about use in conjunction with NSAIDS and aspirin. I am assuming because the SSRI works in similar way, so there is a potential of a compound effect (as to bleeding/coagulation issues). Is this right? And if so, since I am not to be taking aspirin or NSAIDs, should I not take an SSRI either? I don't think my PSP understands the whole spine healing thing and what inhibits recovery. I wonder if I should call the surgeon and double check, since my PCP and surgeon don't communicate to each other.

    Could just be my anxiety working overtime though, I can't tell where the line is sometimes between overthinking something and being a good advocate for myself.
    Meg is Spinewhine
    31 years old with thoracic curve
    Wore Boston brace as teenager, but curve continued to progress.
    Surgery on 12/13/2005 with correction from over 55 degrees to under 25 degrees. (Ya baby!)

    The nitty gritty at:
    http://spinewhine.blogspot.com/

  2. #2
    Join Date
    Mar 2005
    Location
    east coast
    Posts
    359
    SSRI stands for selective seretonin reuptake inhibitor.

    SSRIs work by selectively blocking the seretonin reuptake receptors in the brain so more seretonin is available in the synaptic space for use. Your brain isn't creating more seretonin, it just isn't 'reaborbing' as much.

    The reason for catuion with SSRI + NSAID/aspirin use is due to higher risk of GI bleed. SSRIs cause GI bleed by itself in some people and when a NSAID or asprin is added to the mix it can increase the risk quite a bit.

  3. #3
    Join Date
    Aug 2005
    Location
    Metro-Detroit, Michigan
    Posts
    138
    So combined with my daily coumadin use, there cold be an issue, since I am already on blood thinners and have increased bleeding risk. Sounds like I am calling the Dr...
    Meg is Spinewhine
    31 years old with thoracic curve
    Wore Boston brace as teenager, but curve continued to progress.
    Surgery on 12/13/2005 with correction from over 55 degrees to under 25 degrees. (Ya baby!)

    The nitty gritty at:
    http://spinewhine.blogspot.com/

  4. #4
    Join Date
    Mar 2005
    Location
    east coast
    Posts
    359
    Quote Originally Posted by SpineWhine
    So combined with my daily coumadin use, there cold be an issue, since I am already on blood thinners and have increased bleeding risk. Sounds like I am calling the Dr...
    I vaguely remember reading something about lexapro enhancing the effects of some anticoagulants, but I don't know how true that is and exactly which anticoagulants.

  5. #5
    Join Date
    Sep 2005
    Location
    Tennessee
    Posts
    388
    Your pharmacist might be able to help you with the contra-indications of your meds too.

    I think anxiety problems are an unanticipated side-effect of this huge surgery.. Many people experience them.. including me. I keep a prescription with me at all times to take if a panic attack starts again... It's good to know that i have it there even if i don't use it, it's reassuring.

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