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Thread: Bmp for spine fusion, possible cancer correlation!

  1. #1
    Join Date
    Sep 2009
    Posts
    151

    Bmp for spine fusion, possible cancer correlation!

    My brother, who is a physician assistant, just sent me this article on BMP. Has anybody else have any information about BMP?

    http://www.medpagetoday.com/surgery/orthopedics/21908

    rich

  2. #2
    Join Date
    Aug 2009
    Posts
    1,164
    I spent some time looking at the BMP stuff (my son hasn't had spinal surgery yet, but he did get BMP for jaw surgery recently). I saw the concerns raised about cancer, but I haven't seen any studies to support that. Here's a pretty detailed look at the studies they've done so far - http://www.aaos.org/news/aaosnow/may08/research7.asp

    Most of the other complications are off-label use, particularly BMPs use in the cervical spine, which can cause serious problems. They didn't specify the exact use in the article for the cases where there was bony growth in the spinal column, but they did note that was off-label use as well.

    The only thing I saw in researching it that did concern me (although not for my son) is that apparently it's use in teenagers and women who might become pregnant is also off-label. Maybe that's old information.

    The cozy relationship between the device people and the medical people, though, is very troubling. It makes it that much harder to figure out what's really going on. That said, BMP is widely used by lots and lots of surgeons, and the majority aren't benefiting from it financially. I trust people like Lenke and my son's jaw surgeon to make sense of the materials that they're using. And for adults in pain, the idea of living a life in pain has to beat out the possible risk of cancer. But it would seem to be another caution flag for adults who aren't in pain or progressing to maybe hold off surgery until it's really necessary.
    Last edited by hdugger; 02-28-2011 at 01:15 AM.

  3. #3
    Join Date
    Mar 2009
    Location
    Carmel/Indianapolis
    Posts
    246
    Well, I'm loaded up with BMP. I completely trust Dr Bridwell and just can't believe he would be using BMP if there was any meaningful research showing that it is unsafe.
    Age 56
    Wore a Milwaukee Brace for 3 years in hs
    Fused L4-S1 for high grade spondylolisthesis Jan '09 in Indy
    Thoracic 68
    Surgery Aug 31, 2010 T3 to L1
    Dr Bridwell St Louis
    http://www.scoliosis.org/forum/attac...1&d=1289881696

  4. #4
    Join Date
    Apr 2010
    Location
    Easton PA
    Posts
    182

    Rich,

    Thank you for the information. My surgeon plans on using BMP for my surgery in June, and I do have a history of cancer, so this was especially of interest to me. I will print the article, and show it to my Dr.
    Lori in PA, 52 yrs. old
    T54/L72
    Surgery 6/7/11, T3-S1, all posterior, with pelvic anchors
    Gained 2 inches!
    Dr. Boachie, HSS, NYC
    12/10/13 Hardware Removal for infection
    Lost 2", gained PJK!

  5. #5
    Join Date
    Mar 2009
    Location
    Carmel/Indianapolis
    Posts
    246
    Lori- It will be interesting to hear what Dr Boachie says. Let me know.
    Age 56
    Wore a Milwaukee Brace for 3 years in hs
    Fused L4-S1 for high grade spondylolisthesis Jan '09 in Indy
    Thoracic 68
    Surgery Aug 31, 2010 T3 to L1
    Dr Bridwell St Louis
    http://www.scoliosis.org/forum/attac...1&d=1289881696

  6. #6
    Join Date
    Mar 2005
    Location
    Ukiah CA
    Posts
    891
    rich my surgeon has a big insterts in BMPs in spinal fusions
    Kara
    25
    Brace 4-15-05-5-25-06
    Posterior Spinal Fusion 3-10-10
    T4-L2
    Before 50T
    After 20T

  7. #7
    Join Date
    Apr 2010
    Location
    Easton PA
    Posts
    182
    Lisa- I won't be seeing him again until May, but I will definitely post what he says about it. Lori
    Lori in PA, 52 yrs. old
    T54/L72
    Surgery 6/7/11, T3-S1, all posterior, with pelvic anchors
    Gained 2 inches!
    Dr. Boachie, HSS, NYC
    12/10/13 Hardware Removal for infection
    Lost 2", gained PJK!

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